The group is highly multidisciplinary, with researchers working on synthesis and structural biology, proteomics and cell biology, on in vitro and in vivo systems, often undertaking work in collaboration with labs at Imperial in Medicine, Engineering and Natural Sciences, and groups at institutes and companies across the UK and worldwide. Group membership is also highly diverse - more than 145 researchers have worked in our group over the years, encompassing 28 nationalities.
Staff
Dr Edward Bartlett
Dr Edward Bartlett
Research associate and lab manager (chemical biology)
Daria Berezina
Daria Berezina
Chemical Biology Technician
Erika Bernardini
Erika Bernardini
Tissue culture technician
Dr Efthymios Spyridon Gavriil
Dr Efthymios Spyridon Gavriil
Research associate, medicinal chemistry and cancer drug discovery
Dr Sarah Hassan
Dr Sarah Hassan
Research Associate, previous President's Scholar ICB CDT PhD, protein prenylation in cancer
Dr Benedikt Holbling
Dr Benedikt Holbling
Head of Phenotypic Screening and Operations, Imperial-LMS Drug Discovery Hub
Dr Jack Houghton
Dr Jack Houghton
CRUK research associate, chemical proteomics
Dr Manuel de Jésus Tavares Cornejo
Dr Manuel de Jésus Tavares Cornejo
CRUK research associate, chemical biology and cancer drug discovery
Dr Wouter Kallemeijn
Dr Wouter Kallemeijn
PLRS, chemical biology at the Francis Crick Institute
Amber Pei
Amber Pei
Synthetic Chemistry Technician
Dr Anne Schuhmacher
Dr Anne Schuhmacher
SNSF research associate, protein S-acylation
Dr Masha Shchepinova
Dr Masha Shchepinova
Research associate, GPCR chemical biology (34-36)
PhD students
Frederic Buemi
Frederic Buemi
4th year PhD student, hydrolytic enzymes driving colorectal cancer development (65)
Shreyas Bhatt
Shreyas Bhatt
2nd year ICB CDT PhD, Gut-on-a-chip 4.0 (34, 35, 72)
Zuzanna Jablonska
Zuzanna Jablonska
4th year PhD student (+ MRes), BHF Centre, new therapeutic targets in ischemic heart disease (66)
Vincent Saverat
Vincent Saverat
3rd year PhD (+ MRes), ICB and Merck Sharp & Dohme CDT, developing novel biofunctional probes (64)
Matt White
Matt White
4th year CRUK/ICB PhD student, chemical proteomics and mechanisms of senescence (73)
Shradda Vadodaria
Shradda Vadodaria
3rd year ICB CDT PhD student, covalent inhibition of a small GTPase
Gaseitsiwe Lame Senatla
Gaseitsiwe Lame Senatla
4th year PhD student, Botswana Government scholar, inhibitors of hedgehog acyltransferase (62, 69)
Abigail Iles
Abigail Iles
3rd year EPSRC/MSD ICB CDT PhD student, proximity-based drug-target identification (39, 76)
Xinyue Zhang
Xinyue Zhang
3rd year PhD, Imperial-China Scholarship Council, bifunctional discovery platforms
Thomas Maher
Thomas Maher
3rd year PhD (+ MRes) ICB CDT, development of probes investigating G4 interacting proteins (74, 75)
Jack Dainton
Jack Dainton
2nd year PhD (+ MRes) ICB CDT, high-throughput molecular glue discovery platforms (56)
Anna Kukushkina
Anna Kukushkina
2nd year PhD (+ MRes) ICB CDT, drugging the intractable interactome (75)
Amy McIntosh
Amy McIntosh
2nd year PhD (+ MRes), synthesis of photoactivatable molecular probes (74, 75, 77)
Sofia Philipps
Sofia Philipps
2nd year PhD (+ MRes), ICB CDT, photoswitchable PROTAC technology (39, 57)
Sofia Srdanovic
Sofia Srdanovic
2nd year PhD (+ MRes) ICB CDT, antibody-drug conjugate therapies (78)
Anouk Huyghebaert
Anouk Huyghebaert
1st year ICB CDT/AstraZeneca PhD student, Novel ADC linker technologies
Long-Hung Pham
Long-Hung Pham
1st year PhD (+MRes) ICB CDT, computational analysis of protein allostery
Jiaying Zhuang
Jiaying Zhuang
1st year PhD (+MRes) ICB CDT chemical biology and drug discovery technology for deubiquitinases
Kevin Yeung
Kevin Yeung
1st year PhD (+MRes) ICB CDT new approaches to probe and understand the undruggable proteome
Cecilia Cheng
Cecilia Cheng
1st year PhD, Synthesis and novel applications of DNA encoded libraries for PROTAC discovery (81)
Trudy Glaser
Trudy Glaser
2nd year President's PhD Scholar, ETV5 as a PROTAC target in B-cell ALL (82)
Konstantina Arvaniti
Konstantina Arvaniti
1st year MRes (+PhD) ICB CDT, on-target lead discovery for next-generation antimicrobials (46)
MRes students
Undergraduate Students
Friederike Marte
Friederike Marte
MSci UG student (ETH), protein degradation
Gilles Brunner
Gilles Brunner
MSci UG student (ETH), S-acylation probes
Hannah Peters
Hannah Peters
MSci UG student, molecular glues
Harsimran Sarai
Harsimran Sarai
MSci UG student, HHAT inhibitors
Michael Onoufriou
Michael Onoufriou
MSci UG student, screening of ZDHHC inhibitors
Other members
Roxani Nikoloudaki
Roxani Nikoloudaki
PhD student (writing up)
Alumni
Postdoctoral researchers: 2008: Sasala Wickramasinghe. 2010: Lucia de la Riva Perez. 2011: Dmitry Stetsenko, Vicki Barker, Matt Selby, Ute Brassat. 2012: Will Heal, Victor Goncalves. 2013: Victoria Albrow, Mark Rackham, Zhiyong Yu. 2014: Antonio Konitsiotis, Jennie Hutton. 2015: Goska Broncel, Soo Mei Chee, Kalesh. 2017: Rhiannon Beard, Julia Morales Sanfrutos, Markus Ritzefeld, Inma Perez Dorado. 2018: Remi Serwa, Charlotte Sutherell, Chiara Recchi, Chiara Fabbro. 2019: Aurélien Godinat, Anna Neodo, Scott Lovell, Marc Baggelaar. 2020: Monica Faronato, Tom Lanyon-Hogg. 2021: Ateequllah Hayat, Andrea Goya Grocin, Montse Tersa, Jennie Hutton, Ayesha Tejura (RA), Jasmine Bickel, Andrii Gorelik, Milon Mondal. 2022: Tony Ocasio, Dan Conole, Christelle Soudy, Daniel Lucy, James Sipthorp, Rita Petracca, Ravi Singh. 2023: Sebastian Andrei, Folake Orafidiya, Elena De Vita, Ammar Ahmed. 2024: Patrycja Michalska Dziama, Lior Soday, Josephine Walton.
PhD students: 2009: Panumart Thongyoo. 2010: Gillian Rosenberg. 2011: Jemima Thomas, Tam Dang. 2012: Tayo Olaleye, Lucy Rayner, Alex Berry, Jenny Frueh. 2013: Megan Wright, Manue Thinon. 2014: Chris Douse. 2015: Naoko Masumoto, Paulina Ciepla, Tom Charlton, James Clulow, Andy Bell. 2016: Louis Perdios, Siak Lim, Lisa Storck Saha, Rhiannon Beard, Jenny Ward, Ernie So. 2017: Yunyun Sun, Mostafa Jamshidiha, Greg Craven. 2018: Wenye Zhao, Roman Fedoryshchak, Foteini Tzakoniati, Shao-Ju (Ryan) Lu. 2019: Jessica Shen, Charlie Saunders, Theo Flack, Mladen Stojanovic, Scott Lovell, Eloise Morecroft, Will Joyce, Anja Schlott, Gregor Lueg. 2020: Jasmine Bickel, Kate Hadavizadeh, Nattawadee Panyain, Andrea Goya Grocin, Miha Homsak, Ryan Howard, Cassandra Kennedy. 2022: Leran Zhang, Henry Benns, Simeon Draganov, Emma Couves. 2023: Ana Losada De La Lastra, Cyrille Kounde, Joe Tuersley, Delia Brustur, Miruna Androniciuc, Josh Linfoot, Qisi Zhang, Sarah Hassan. 2024: Thomas Jackson, Jack Williams, Michael Gruet, Chotima Seripracharat.
MRes students: 2008: Pinar Tulay, Martyna Snopek, Kavita Ramji. 2009: Antoine Delmotte. 2010: Kim Williams, Lucy Esteve, Janet Tsang. 2011: Dani Monteil. 2012: Tiffany Teng, Nino Gaphrindashivili. 2013: Liji Huang, George Bodakh, June Lim, Xiaoyi Wang, Eric Lee. 2014: Yuchen Zhao. 2015: Larissa See, Runzhong Fu, Jason Mak, Sandi Botonjic, Giovanna Morsiani. 2016: Juan Cuadrado, Lerui Guo, Zuzana Hodakova, Miriam Lyons, Niall McLoughlin, Sebastian Soh, Congyi Xu, Handa Zhang. 2017: Rania Al Janabi, Daniel Fernandez Llaneza, Isabella Kaczmarczyk, Sebastian Oehler, Carine Lim, Leran Zhang, Chiara Cecconello. 2018: Irphane Ariff, Sofia Chalkiadaki, Declan Cook, Nicole Deacon-Smith, Sarah Hassan, Kai Hove, Caitlin Jie, Sofia Lachiondo, Bowen Ma, Pasin Mapaisansin, Balazs Pogranyi, Xinzhu Wang. 2019: Billy Baxter, M. Juncal Calvo, Jonathan Davies, Leigh-Anne Gavin, Arzish Haqqee, Thomas Jackson, Callum Johnston, Javier Molina-Bermejo, Jingxing Qiu, Tilly Shackley, Ceire Wincott, Jinwang Yuan. 2020: Debraj Chowdhury, Amrita Date, Lisa Dollhopf, Mathias Fagbemi, Jeff Guo, Ming Huang, Qinxue Kong, Yuxin Liu, Nelli Morgulchik, Nikitas Ostrovitsa, Esther Perez-Barreiro, Panagiota Sarri, Emilia Taylor, Ayesha Tejura, Ioanna Thanasi, Pinqi Wang. 2021: Konstantina Arvaniti, Audrey Dausse, Matthew Dooley, Anusha Gupta, Abigail Iles, Aristo Kong, Caitlin Leo, Xiwen Ma, Amina Nigmatulina, Max Phillips, Jonathan Rockman, Gaseitsiwe Lame Senatla, David Sharp, Shradda Vadodaria, Xinyue Zhang, Peihao Zhao. 2022: Beatrice Bizzotto, Fabiana Ferreira Duarte, Nathan Hardingham, Yaru Meng, Aaron Mothersole, Olivia Ramsay, Haozhe Xiao, Hongyu Ye, Minao Zhang, Kai Zheng. 2023: Khadija Babiker, Najma Hassan, Jaskirat Kaur, Siyu Liang, Silvia Vannini, Yurui Yang. 2024: Aoki Ardisson, Omar Benchekroun, Will Banyard, Hina Sakakibara, Emma Stullerova, Lydia Papagora, Yujin Luo, Ellie Storr, Molly Sharman, Pablo Lasso.
Undergraduate project/placement students: 2006: Helen Mcleod. 2007: Will Tomlinson, Katherine Elvira, Camille Bonomelli. 2008: James Sudlow. 2009: Irvine Howson, Vlad Turek, Sara Bessin. 2010: Aled Williams, Amanda Cheung, Sascha Yousefi, Genshi Chen. 2011: Machi Panteli, Brian Wilson, Timo Voelker, Wenlin Zhang, Nina Vrielink, Julia Gonzales Hernandes, Sibyl Sheppard. 2012: Enrico Fantoni, Jenny Mizen, Solene Batut, Klaudia Cybulska, Boon Kiat Lee. 2013: Wai Peng Leong, Alice Huynh, Ben Chappell, Sabrina Maas, Chrystalla Constantinou, Will Whitehurst, Saphia Matthew. 2014: Olivia Boyd, James Davies, Xavier Wezen, Shuang Liu, Wouter Mooij, Niall McLoughlin. 2015: Tiffany Chan, Shuang Liu, Markus Artelsmair, Joel Fauser. 2016: Yuen Chow, Michelle Tan, Jenny Samphire, Suk Tan, Annina Burhop, Edward Ou, Alex Bakker, Christine Wu. 2017: Aditya Raymond Thawani, Rhian Hendley, Ana Losada de la Lastra, Dongxun Lyu, Angela Sun. 2019: Stef Bannink, Edward Will, Jianjun (JJ) Ren, Alana Dastous, Camilla Ferro. 2020: Tristan Kovacic, Joshua Newington. 2021: Yongyin (Dorene) Chen, Yicheng Wang. 2022: Fawaz Raja, Anna Kukushkina, Minqi Pan, Ryota Nakao, Haiyang He, Jiaying Zhuang. 2023: Capucine Solier, Priantha Pretheshan, Annabel Chatwin, Gemma Wallis, Tim Hindges. 2024: Keyu Zhu, Sam Liu, Amber Pei, TT Zhang, Aisha Animashaun, Chloe Huang, Kira Scobel, Yudi Lu, Luke Szczygielski.
Visiting researchers: 2015: Dr Kasia Blewska (Lodz, COST network), Dany Pechalrieu (Toulouse, COST network). 2016: Daniela Glatzova (University of Prague, RSC mobility award). 2018: Wenhua Chen (CSC Scholarship), Elena De Vita (DKFZ, German Cancer Research Center). 2019: Michael Baek (University of Copenhagen). 2020: Jing Han (Institute of Chemistry, Chinese Academy of Sciences), Danai Kati (UCL). 2021: Dr María Maneiro Rey (Xunta de Galicia Fellow). 2022: André Luz (Universidade de Lisboa), Dr Rishi Shah (GSK).
Collaborating labs and organisations
1. Peter O'Hare (Virology); 2. The Francis Crick Institute; 3. Tony Magee (NHLI); 4. Pfizer Neusentis; 5. Medicines for Malaria Venture; 6. Imperial Innovations; 7. Matilda Katan (UCL); 8. Paul French (Laser Physics); 9. Beata Wojciak-Stothard (Medicine); 10. Gad Frankel (Molecular Microbiology); 11. Tony Gee (KCL); 12. Colin Turnbull (Plant Physiology); 13. David Mann (Life Sciences); 14. Ernesto Cota (Structural Biology); 15. Institute of Cancer Research; 16. David Klug (Chemistry); 17. Reiko Tanaka (Bioengineering); 18. Syngenta; 19. Alan Armstrong (Chemistry); 20. Jamie Scott, Jeffrey Johannes (AstraZeneca); 21. Oscar Ces (Chemistry); 22. Jake Baum (Parasitology); 23. Xiaodong Zhang (Structural Biology); 24. Chiara Recchi (Oncology); 25. Keith Willison (Chemistry); 26. Hani Gabra (Oncology); 27. Tony Holder (Crick); 28. Dinis Calado (Crick); 29. Anna Barnard (Chemistry); 30. Doryen Bubeck (Structural Biology); 31. Charlotte Dodson (Biophysics); 32. Edgar Deu (Crick); 33. Alex Lyons (Medicine, NHLI); 34. Gary Frost (Medicine); 35. Aylin Hanyaloglu (Medicine); 36. Nestlé; 37. Susana Godinho (The Barts Cancer Institute, London); 38. Luiz Pedro Carvalho (Crick); 39. Avinash Shenoy (Microbiology); 40. Genentech; 41. John Harling (GSK); 42. Marcel Muelbaier (Cellzome/GSK); 43. Eric Aboagye (Surgery and Cancer); 44. Charlotte Bevan (Surgery and Cancer); 45. Hani Gabra (Surgery and Cancer); 46. Matt Child (Life Sciences); 47. Pete DiMaggio (Chemical Engineering); 48. Jean-Paul Vincent (Crick); 49. Evgen Pharma; 50. Julian Downward (Crick); 51. Vania Braga (Medicine); 52. Heptares; 53. Alan Spivey (Chemistry); 54. Jim Norman (CRUK, Beatson Institute, Glasgow); 55. Hector Keun (Surgery and Cancer); 56. Louise Walport (Crick); 57. Matthew Fuchter (Chemistry); 58. Rui Moreira, Cecília M. P. Rodrigues (Universidade de Lisboa); 59. Iain McNeish (Surgery and Cancer); 60. Myricx Pharma Ltd; 61. Dorian Haskard (Medicine); 62. Christian Siebold (Oxford); 63. Lou Chesler (ICR); 64. Mark Rackham (MSD); 65. Rachael Barry (Medicine); 66. Michela Noseda (Medicine); 67. Ben Perry (DNDi); 68. Andrew Edwards (Medicine); 69. Tom Lanyon-Hogg (Oxford); 70. David Gray (Dundee); 71. Steve Matthews (Structural Biology); 72. Joshua Edel (Chemistry); 73. Jesús Gil (Medicine); 74. Ramón Vilar Compte (Chemistry); 75. Marco Di Antonio (Chemistry); 76. James Bull (Chemistry); 77. David Hewings (Vertex Pharm. Ltd); 78. ADC Therapeutics; 79. Konstantinos Beis (Life Sciences); 80. David Carling (Medicine); 81. Xiaoyu Li group (HKU); 82. Niklas Feldhahn (Medicine); 83. Santiago Vernia (MRC); 84. Laurent Knerr (AZ); 85. Gerald Larrouy-Maumus (Microbiology).
Contact
Prof. Ed Tate
GSK Chair in Chemical Biology
Department of Chemistry
Molecular Sciences Research Hub, White City Campus,
82 Wood Lane, London, W12 0BZ
e.tate@imperial.ac.uk
Tel: +44 (0)20 759 + ext 43752 or 45821